YajL, Prokaryotic Homolog of Parkinsonism-associated Protein DJ-1, Functions as a Covalent Chaperone for Thiol Proteome

YajL is the closest Escherichia coli homolog of the Parkinsonism-associated protein DJ-1, a multifunctional oxidative stress response protein whose biochemical function remains unclear. We recently reported the aggregation of proteins in a yajL mutant in an oxidative stress-dependent manner and that...

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Main Authors: Le, Hai-Tuong, Gautier, Valérie, Kthiri, Fatoum, Malki, Abderrahim, Messaoudi, Nadia, Mihoub, Mouadh, Landoulsi, Ahmed, An, Young Jun, Cha, Sun-Shin, Richarme, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Synthesis and Degradation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285355/
https://ncbi.nlm.nih.gov/pubmed/22157000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299198
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