Translational Defects in a Mutant Deficient in YajL, the Bacterial Homolog of the Parkinsonism-Associated Protein DJ-1

We report here that YajL is associated with ribosomes and interacts with many ribosomal proteins and that a yajL mutant of Escherichia coli displays decreased translation accuracy, as well as increased dissociation of 70S ribosomes into 50S and 30S subunits after oxidative stress.

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Detalhes bibliográficos
Main Authors: Kthiri, Fatoum, Gautier, Valérie, Le, Hai-Tuong, Prère, Marie-Françoise, Fayet, Olivier, Malki, Abderrahim, Landoulsi, Ahmed, Richarme, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981216/
https://ncbi.nlm.nih.gov/pubmed/20889753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01077-10
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