Metastasis-associated Protein 1 Drives Tumor Cell Migration and Invasion through Transcriptional Repression of RING Finger Protein 144A

Metastasis-associated protein 1 (MTA1), a component of the nucleosome-remodeling and histone deacetylase complex, is widely up-regulated in human cancers and significantly correlated with tumor invasion and metastasis, but the mechanisms involved remain largely unknown. Here, we report that MTA1 tra...

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Hauptverfasser: Marzook, Hezlin, Li, Da-Qiang, Nair, Vasudha S., Mudvari, Prakriti, Reddy, Sirigiri Divijendra Natha, Pakala, Suresh B., Santhoshkumar, T. R., Pillai, M. Radhakrishna, Kumar, Rakesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285335/
https://ncbi.nlm.nih.gov/pubmed/22184113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314088
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