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Heparin-induced Leukocytosis Requires 6-O-Sulfation and Is Caused by Blockade of Selectin- and CXCL12 Protein-mediated Leukocyte Trafficking in Mice

Leukocytosis refers to an increase in leukocyte count above the normal range in the blood and is a common laboratory finding in patients. In many cases, the mechanisms underlying leukocytosis are not known. In this study, we examined the effects, the structural determinants, and the underlying mecha...

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Autori principali: Zhang, Siyuan, Condac, Eduard, Qiu, Hong, Jiang, Junlin, Gutierrez-Sanchez, Gerardo, Bergmann, Carl, Handel, Tracy, Wang, Lianchun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285330/
https://ncbi.nlm.nih.gov/pubmed/22194593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314716
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