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Macro Histone H2A1.2 (MacroH2A1) Protein Suppresses Mitotic Kinase VRK1 during Interphase

VRK1-mediated phosphorylation of histone H3 should be restricted in mitosis for consistent cell cycling, and defects in this process trigger cellular catastrophe. However, an interphasic regulator against VRK1 has not been actually investigated so far. Here, we show that the histone variant macrodom...

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Detalhes bibliográficos
Main Authors: Kim, Wanil, Chakraborty, Goutam, Kim, Sangjune, Shin, Joon, Park, Choon-Ho, Jeong, Min-Woo, Bharatham, Nagakumar, Yoon, Ho Sup, Kim, Kyong-Tai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285308/
https://ncbi.nlm.nih.gov/pubmed/22194607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.281709
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