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The RhoGAP domain of CYK-4 has an essential role in RhoA activation

Cytokinesis in animal cells is mediated by a cortical actomyosinbased contractile ring. The GTPase RhoA is a critical regulator of this process as it activates both non-muscle myosin and a nucleator of actin filaments [1]. The site at which active RhoA and its effectors accumulate is controlled by t...

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Autors principals: Loria, Andy, Longhini, Katrina M., Glotzer, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285270/
https://ncbi.nlm.nih.gov/pubmed/22226748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.12.019
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