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The RhoGAP domain of CYK-4 has an essential role in RhoA activation
Cytokinesis in animal cells is mediated by a cortical actomyosinbased contractile ring. The GTPase RhoA is a critical regulator of this process as it activates both non-muscle myosin and a nucleator of actin filaments [1]. The site at which active RhoA and its effectors accumulate is controlled by t...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285270/ https://ncbi.nlm.nih.gov/pubmed/22226748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.12.019 |
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