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Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF Complex to Initiate Cleavage Furrow Formation

To complete cell division with high fidelity, cytokinesis must be coordinated with chromosome segregation. Mammalian Polo-like kinase 1, Plk1, may function as a critical link because it is required for chromosome segregation and establishment of the cleavage plane following anaphase onset. A central...

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Autors principals: Wolfe, Benjamin A., Takaki, Tohru, Petronczki, Mark, Glotzer, Michael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680334/
https://ncbi.nlm.nih.gov/pubmed/19468300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000110
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