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Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG

Spinosyns A and D (spinosad), like many other complex polyketides, are tailored near the end of their biosyntheses through the addition of sugars. SpnG, which catalyzes their 9-OH rhamnosylation, is also capable of adding other monosaccharides to the spinosyn aglycone (AGL) from TDP-sugars; however,...

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Autors principals: Isiorho, Eta A., Liu, Hung-wen, Keatinge-Clay, Adrian T.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285110/
https://ncbi.nlm.nih.gov/pubmed/22283226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201860q
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