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Functional Characterization and Substrate Specificity of Spinosyn Rhamnosyltransferase by in Vitro Reconstitution of Spinosyn Biosynthetic Enzymes

Spinosyn, a potent insecticide, is a novel tetracyclic polyketide decorated with d-forosamine and tri-O-methyl-l-rhamnose. Spinosyn rhamnosyltransferase (SpnG) is a key biocatalyst with unique sequence identity and controls the biosynthetic maturation of spinosyn. The rhamnose is critical for the sp...

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Detalhes bibliográficos
Main Authors: Chen, Yi-Lin, Chen, Yi-Hsine, Lin, Yu-Chin, Tsai, Kuo-Chung, Chiu, Hsien-Tai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652332/
https://ncbi.nlm.nih.gov/pubmed/19126547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808441200
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