Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

BACKGROUND: Malignant ovarian disease is characterised by high rates of mortality due to high rates of recurrent chemoresistant disease. Anecdotal evidence indicates this may be due to chemoresistant properties of cancer stem cells (CSCs). However, our understanding of the role of CSCs in recurrent...

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Autori principali: Gallagher, Michael F, Heffron, Cynthia CBB, Laios, Alexandros, O'Toole, Sharon A, Ffrench, Brendan, Smyth, Paul C, Flavin, Richard J, Elbaruni, Salah A, Spillane, Cathy D, Martin, Cara M, Sheils, Orla M, O'Leary, John J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285047/
https://ncbi.nlm.nih.gov/pubmed/22260314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-5-2
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