Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

BACKGROUND: Malignant ovarian disease is characterised by high rates of mortality due to high rates of recurrent chemoresistant disease. Anecdotal evidence indicates this may be due to chemoresistant properties of cancer stem cells (CSCs). However, our understanding of the role of CSCs in recurrent...

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Main Authors: Gallagher, Michael F, Heffron, Cynthia CBB, Laios, Alexandros, O'Toole, Sharon A, Ffrench, Brendan, Smyth, Paul C, Flavin, Richard J, Elbaruni, Salah A, Spillane, Cathy D, Martin, Cara M, Sheils, Orla M, O'Leary, John J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285047/
https://ncbi.nlm.nih.gov/pubmed/22260314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-5-2
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