Loss of Proteostatic Control as a Substrate for Atrial Fibrillation: A Novel Target for Upstream Therapy by Heat Shock Proteins

Atrial fibrillation (AF) is the most common, sustained clinical tachyarrhythmia associated with significant morbidity and mortality. AF is a persistent condition with progressive structural remodeling of the atrial cardiomyocytes due to the AF itself, resulting in cellular changes commonly observed...

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Autors principals: Meijering, Roelien A. M., Zhang, Deli, Hoogstra-Berends, Femke, Henning, Robert H., Brundel, Bianca J. J. M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284689/
https://ncbi.nlm.nih.gov/pubmed/22375124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00036
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