Reduction of Ethanol Consumption in Alcohol-Preferring Rats by Dual Expression Gene Transfer

Aims: To mimic, in an animal model of alcoholism, the protective phenotype against alcohol consumption observed in humans carrying a fast alcohol dehydrogenase (ADH1B*2) and an inactive aldehyde dehydrogenase (ALDH2*2). Methods: We developed a multiple expression cassette adenoviral vector (AdV-ADH/...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Rivera-Meza, Mario, Quintanilla, María Elena, Tampier, Lutske
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
Pharmacology and Cell Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284687/
https://ncbi.nlm.nih.gov/pubmed/22214999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/agr161
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky