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Reduction of Ethanol Consumption in Alcohol-Preferring Rats by Dual Expression Gene Transfer
Aims: To mimic, in an animal model of alcoholism, the protective phenotype against alcohol consumption observed in humans carrying a fast alcohol dehydrogenase (ADH1B*2) and an inactive aldehyde dehydrogenase (ALDH2*2). Methods: We developed a multiple expression cassette adenoviral vector (AdV-ADH/...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3284687/ https://ncbi.nlm.nih.gov/pubmed/22214999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/agr161 |
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