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G Protein βγ-Subunit Signaling Mediates Airway Hyperresponsiveness and Inflammation in Allergic Asthma

Since the Gβγ subunit of Gi protein has been importantly implicated in regulating immune and inflammatory responses, this study investigated the potential role and mechanism of action of Gβγ signaling in regulating the induction of airway hyperresponsiveness (AHR) in a rabbit model of allergic asthm...

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Main Authors: Nino, Gustavo, Hu, Aihua, Grunstein, Judith S., McDonough, Joseph, Kreiger, Portia A., Josephson, Maureen B., Choi, John K., Grunstein, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284547/
https://ncbi.nlm.nih.gov/pubmed/22384144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032078
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