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Brain-derived neurotrophic factor receptor TrkB exists as a preformed dimer in living cells
BACKGROUND: Neurotrophins (NTs) and their receptors play crucial roles in the development, functions and maintenance of nervous systems. It is widely believed that NT-induced dimerization of the receptors initiates the transmembrane signaling. However, it is still controversial whether the receptor...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3284413/ https://ncbi.nlm.nih.gov/pubmed/22269274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-7-2 |
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