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Brain-derived neurotrophic factor receptor TrkB exists as a preformed dimer in living cells

BACKGROUND: Neurotrophins (NTs) and their receptors play crucial roles in the development, functions and maintenance of nervous systems. It is widely believed that NT-induced dimerization of the receptors initiates the transmembrane signaling. However, it is still controversial whether the receptor...

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Detalhes bibliográficos
Main Authors: Shen, Jianying, Maruyama, Ichiro N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284413/
https://ncbi.nlm.nih.gov/pubmed/22269274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-7-2
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