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Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei
The metaphase-anaphase transition is orchestrated through proteolysis of numerous proteins by an ubiquitin protein ligase called the Anaphase-promoting complex or cyclosome (APC/C)(1). A crucial aspect of this process is sister chromatid separation, which is thought to be mediated by separase, a thi...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3284228/ https://ncbi.nlm.nih.gov/pubmed/20081838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2018 |
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