Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains

Vascular damage caused by Shiga toxin (Stx)-producing Escherichia coli is largely mediated by Stxs, which in particular, injure microvascular endothelial cells in the kidneys and brain. The majority of Stxs preferentially bind to the glycosphingolipid (GSL) globotriaosylceramide (Gb3Cer) and, to a l...

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Detalhes bibliográficos
Main Authors: Betz, Josefine, Bielaszewska, Martina, Thies, Andrea, Humpf, Hans-Ulrich, Dreisewerd, Klaus, Karch, Helge, Kim, Kwang S., Friedrich, Alexander W., Müthing, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284156/
https://ncbi.nlm.nih.gov/pubmed/21252262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M010819
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