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DNA Replication Fading As Proliferating Cells Advance in Their Commitment to Terminal Differentiation

Terminal differentiation is the process by which cycling cells stop proliferating to start new specific functions. It involves dramatic changes in chromatin organization as well as gene expression. In the present report we used cell flow cytometry and genome wide DNA combing to investigate DNA repli...

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Detalhes bibliográficos
Main Authors: Estefanía, Monturus Ma., Ganier, Olivier, Hernández, Pablo, Schvartzman, Jorge B., Mechali, Marcel, Krimer, Dora B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283920/
https://ncbi.nlm.nih.gov/pubmed/22359734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00279
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