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Topological locking restrains replication fork reversal

Two-dimensional agarose gel electrophoresis, psoralen cross-linking, and electron microscopy were used to study the effects of positive supercoiling on fork reversal in isolated replication intermediates of bacterial DNA plasmids. The results obtained demonstrate that the formation of Holliday-like...

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Detalhes bibliográficos
Main Authors: Fierro-Fernández, Marta, Hernández, Pablo, Krimer, Dora B., Stasiak, Andrzej, Schvartzman, Jorge B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780069/
https://ncbi.nlm.nih.gov/pubmed/17242356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609204104
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