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Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control

The covalent modification of proteins with ubiquitin is required for accurate cell division in all eukaryotes. Ubiquitylation depends on an enzymatic cascade, in which E3 enzymes recruit specific substrates for modification. Among ~600 human E3s, the SCF (Skp1–cullin1–F-box) and the APC/C (anaphase-...

詳細記述

保存先:
書誌詳細
主要な著者: Mocciaro, Annamaria, Rape, Michael
フォーマット: Artigo
言語:Inglês
出版事項: Company of Biologists 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283867/
https://ncbi.nlm.nih.gov/pubmed/22357967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.091199
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