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Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control
The covalent modification of proteins with ubiquitin is required for accurate cell division in all eukaryotes. Ubiquitylation depends on an enzymatic cascade, in which E3 enzymes recruit specific substrates for modification. Among ~600 human E3s, the SCF (Skp1–cullin1–F-box) and the APC/C (anaphase-...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3283867/ https://ncbi.nlm.nih.gov/pubmed/22357967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.091199 |
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