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Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations
The serotonin (5-HT) transporter (SERT) plays an important role in the termination of 5-HT-mediated neurotransmission by transporting 5-HT away from the synaptic cleft and into the presynaptic neuron. In addition, SERT is the main target for antidepressant drugs, including the selective serotonin re...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer-Verlag
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3283764/ https://ncbi.nlm.nih.gov/pubmed/21670993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-011-1133-1 |
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