The Mechanical Behavior of Mutant K14-R125P Keratin Bundles and Networks in NEB-1 Keratinocytes

Epidermolysis bullosa simplex (EBS) is an inherited skin-blistering disease that is caused by dominant mutations in the genes for keratin K5 or K14 proteins. While the link between keratin mutations and keratinocyte fragility in EBS patients is clear, the exact biophysical mechanisms underlying cell...

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Detalhes bibliográficos
Main Authors: Beriault, Daniel R., Haddad, Oualid, McCuaig, John V., Robinson, Zachary J., Russell, David, Lane, E. Birgitte, Fudge, Douglas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283645/
https://ncbi.nlm.nih.gov/pubmed/22363617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031320
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