The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro

Keratin filaments arise from the copolymerization of type I and II sequences, and form a pancytoplasmic network that provides vital mechanical support to epithelial cells. Keratins 5 and 14 are expressed as a pair in basal cells of stratified epithelia, where they occur as bundled arrays of filament...

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Main Authors: Bousquet, Olivier, Ma, Linglei, Yamada, Soichiro, Gu, Changhong, Idei, Toshihiro, Takahashi, Kenzo, Wirtz, Denis, Coulombe, Pierre A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150872/
https://ncbi.nlm.nih.gov/pubmed/11724817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200104063
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