Oligonucleotide inhibition of IL2R alpha mRNA transcription by promoter region collinear triplex formation in lymphocytes.

The promoter region of the IL2R alpha gene 5' flanking sequence contains enhancer elements crucial for binding nuclear factors which upregulate transcription following T lymphocyte activation. A 3' exonuclease resistant oligonucleotide (3'A-IL28p, terminated by a free amine group at its 3' end) was...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Orson, F M, Thomas, D W, McShan, W M, Kessler, D J, Hogan, M E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1991
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.12.3435
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!