Oligonucleotide inhibition of IL2R alpha mRNA transcription by promoter region collinear triplex formation in lymphocytes.

The promoter region of the IL2R alpha gene 5' flanking sequence contains enhancer elements crucial for binding nuclear factors which upregulate transcription following T lymphocyte activation. A 3' exonuclease resistant oligonucleotide (3'A-IL28p, terminated by a free amine group at its 3' end) was...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Orson, F M, Thomas, D W, McShan, W M, Kessler, D J, Hogan, M E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1991
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.12.3435
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