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Constraints on genes shape long-term conservation of macro-synteny in metazoan genomes

BACKGROUND: Many metazoan genomes conserve chromosome-scale gene linkage relationships (“macro-synteny”) from the common ancestor of multicellular animal life [1-4], but the biological explanation for this conservation is still unknown. Double cut and join (DCJ) is a simple, well-studied model of ne...

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Detalhes bibliográficos
Main Authors: Lv, Jie, Havlak, Paul, Putnam, Nicholas H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283319/
https://ncbi.nlm.nih.gov/pubmed/22151646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S9-S11
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