LDL-apheresis depletes apoE-HDL and pre-β1-HDL in familial hypercholesterolemia: relevance to atheroprotection

Subnormal HDL-cholesterol (HDL-C) and apolipoprotein (apo)AI levels are characteristic of familial hypercholesterolemia (FH), reflecting perturbed intravascular metabolism with compositional anomalies in HDL particles, including apoE enrichment. Does LDL-apheresis, which reduces HDL-cholesterol, apo...

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Detalhes bibliográficos
Main Authors: Orsoni, Alexina, Saheb, Samir, Levels, Johannes H. M., Dallinga-Thie, Geesje, Atassi, Marielle, Bittar, Randa, Robillard, Paul, Bruckert, Eric, Kontush, Anatol, Carrié, Alain, Chapman, M. John
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Patient-Oriented and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283261/
https://ncbi.nlm.nih.gov/pubmed/21957200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P016816
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