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A YAC contig across the fragile X site defines the region of fragility.

The fragile X syndrome is a common cause of mental retardation and is associated with a fragile site at Xq27.3 (FRAXA). Recently, evidence has been presented for the role of methylation and genomic imprinting in the expression of the disease. We have identified a site of methylation in patients by l...

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Détails bibliographiques
Auteurs principaux: Hirst, M C, Rack, K, Nakahori, Y, Roche, A, Bell, M V, Flynn, G, Christadoulou, Z, MacKinnon, R N, Francis, M, Littler, A J
Format: Artigo
Langue:Inglês
Publié: 1991
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC328323/
https://ncbi.nlm.nih.gov/pubmed/2062644
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