A53T-alpha-synuclein-overexpression in the mouse nigrostriatal pathway leads to early increase of 14-3-3 epsilon and late increase of GFAP

Parkinson’s disease (PD) is a neurodegenerative disorder frequent at old age characterized by atrophy of the nigrostriatal projection. Overexpression and A53T-mutation of the presynaptic, vesicle-associated chaperone alpha-synuclein are known to cause early-onset autosomal dominant PD. We previously...

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Detalhes bibliográficos
Main Authors: Kurz, Alexander, May, Caroline, Schmidt, Oliver, Müller, Thorsten, Stephan, Christian, Meyer, Helmut E., Gispert, Suzana, Auburger, Georg, Marcus, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2011
Assuntos:
Basic Neurosciences, Genetics and Immunology - Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282907/
https://ncbi.nlm.nih.gov/pubmed/21960009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-011-0717-3
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