Inactivation of Tetrahymena rRNA self-splicing by cis-platin proceeds through dissociable complexes.

The anti-cancer drug cis-diamminedichloroplatinum (II) (cis-DDP) reacted with Tetrahymena self-splicing rRNA ribozyme, causing loss of self-splicing activity and formation of a number of platinated RNA species. The formation of one distinct platinated product, migrating at an apparent size of 2400 n...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Danenberg, P V, Shea, L C, Danenberg, K D, Horikoshi, T
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1991
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328280/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.11.3123
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