iPLA(2)β Overexpression in Smooth Muscle Exacerbates Angiotensin II-Induced Hypertension and Vascular Remodeling

OBJECTIVES: Calcium independent group VIA phospholipase A(2) (iPLA(2)β) is up-regulated in vascular smooth muscle cells in some diseases, but whether the up-regulated iPLA(2)β affects vascular morphology and blood pressure is unknown. The current study addresses this question by evaluating the basal...

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Detalhes bibliográficos
Main Authors: Calderon, Lindsay E., Liu, Shu, Su, Wen, Xie, Zhongwen, Guo, Zhenheng, Eberhard, Wanda, Gong, Ming C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282780/
https://ncbi.nlm.nih.gov/pubmed/22363752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031850
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