Steady state kinetics and inhibition of HIV-1 reverse transcriptase by a non-nucleoside dipyridodiazepinone, BI-RG-587, using a heteropolymeric template.

Steady state kinetics and inhibition by a dipyridodiazepinone of the reverse transcriptase from human immunodeficiency virus type 1 (HIV) were studied using a heteropolymeric RNA template with a sequence from the authentic initiation site on the HIV genome. For addition of the first deoxynucleotide...

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Autori principali: Kopp, E B, Miglietta, J J, Shrutkowski, A G, Shih, C K, Grob, P M, Skoog, M T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC328267/
https://ncbi.nlm.nih.gov/pubmed/1711678
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