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A general method for the synthesis of 3'-sulfhydryl and phosphate group containing oligonucleotides.

The syntheses are described of polymer supports useful for the synthesis of 3'-partially protected sulfhydryl, free sulfhydryl or phosphate group containing oligonucleotides. The supports are compatible with established phosphoramidite chemistry of oligonucleotide synthesis giving rise to oligo...

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Bibliografiske detaljer
Main Authors: Gupta, K C, Sharma, P, Kumar, P, Sathyanarayana, S
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC328265/
https://ncbi.nlm.nih.gov/pubmed/2057359
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