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DNA superhelicity affects the formation of transcription preinitiation complex on eukaryotic genes differently.

In vitro transcription was reconstituted with HeLa cell transcription factors and RNA polymerase II, which were essentially free from DNA topoisomerase activities. DNA templates with defined negative superhelical densities were tested for transcription activity. Transcription of the Bombyx mori fibr...

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Detalhes bibliográficos
Main Authors: Mizutani, M, Ura, K, Hirose, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC328250/
https://ncbi.nlm.nih.gov/pubmed/1647522
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