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Effects of BRCA1 and BRCA2 mutations on female fertility

Women with BRCA1/2 mutations have a significantly higher lifetime risk of developing breast or ovarian cancer. We suggest that female mutation carriers may have improved fitness owing to enhanced fertility relative to non-carriers. Here we show that women who are carriers of BRCA1/2 mutations living...

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Detalhes bibliográficos
Main Authors: Smith, Ken R., Hanson, Heidi A., Mineau, Geraldine P., Buys, Saundra S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282366/
https://ncbi.nlm.nih.gov/pubmed/21993507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2011.1697
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