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Effects of BRCA1 and BRCA2 mutations on female fertility
Women with BRCA1/2 mutations have a significantly higher lifetime risk of developing breast or ovarian cancer. We suggest that female mutation carriers may have improved fitness owing to enhanced fertility relative to non-carriers. Here we show that women who are carriers of BRCA1/2 mutations living...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282366/ https://ncbi.nlm.nih.gov/pubmed/21993507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2011.1697 |
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