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IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils
IL-33 activates eosinophils directly via the ST2 receptor. Like IL-5, IL-33 induces eosinophilia and eosinophilic airway inflammation in mouse models and primes human eosinophil responses. Previously, we reported that IL-5 priming enhances Siglec-8 mediated mitochondrial and reactive oxygen species...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282301/ https://ncbi.nlm.nih.gov/pubmed/22079334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2011.10.007 |
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