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Characterization of P-Rex1 for its role in fMet-Leu-Phe induced superoxide production in reconstituted COS(phox) cells
P-Rex1 (Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1) is a Rac-specific guanine nucleotide exchange factor activated by Gβγ subunits and by PtdIns((3,4,5))P(3). Recent studies indicate that P-Rex1 plays an important role in signaling downstream of neutrophil chemoattractant rec...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282168/ https://ncbi.nlm.nih.gov/pubmed/20074642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2010.01.001 |
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