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Characterization of P-Rex1 for its role in fMet-Leu-Phe induced superoxide production in reconstituted COS(phox) cells

P-Rex1 (Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1) is a Rac-specific guanine nucleotide exchange factor activated by Gβγ subunits and by PtdIns((3,4,5))P(3). Recent studies indicate that P-Rex1 plays an important role in signaling downstream of neutrophil chemoattractant rec...

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Bibliographic Details
Main Authors: Nie, Baoming, Cheng, Ni, Dinauer, Mary C., Ye, Richard D.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282168/
https://ncbi.nlm.nih.gov/pubmed/20074642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2010.01.001
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