Rare Copy Number Variants in Tourette Syndrome Disrupt Genes in Histaminergic Pathways and Overlap with Autism

BACKGROUND: Studies of copy number variation (CNV) have successfully characterized loci and molecular pathways involved in a range of neuropsychiatric conditions. We conducted an analysis of rare CNVs in Tourette Syndrome (TS) to identify novel risk regions and relevant molecular pathways, evaluate...

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Main Authors: Fernandez, Thomas V, Sanders, Stephan J, Yurkiewicz, Ilana R, Ercan-Sencicek, A. Gulhan, Kim, Young-Shin, Fishman, Daniel O, Raubeson, Melanie J, Song, Youeun, Yasuno, Katsuhito, Ho, Winson SC, Bilguvar, Kaya, Glessner, Joseph, Chu, Su Hee, Leckman, James F., King, Robert A, Gilbert, Donald L, Heiman, Gary A, Tischfield, Jay A, Hoekstra, Pieter J, Devlin, Bernie, Hakonarson, Hakon, Mane, Shrikant M, Günel, Murat, State, Matthew W
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282144/
https://ncbi.nlm.nih.gov/pubmed/22169095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.09.034
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