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Incidence and Risk of QTc Interval Prolongation among Cancer Patients Treated with Vandetanib: A Systematic Review and Meta-analysis

BACKGROUND: Vandetanib is a multikinase inhibitor that is under assessment for the treatment of various cancers. QTc interval prolongation is one of the major adverse effects of this drug, but the reported incidence varies substantially among clinical trials. We performed a systematic review and met...

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Detalhes bibliográficos
Main Authors: Zang, Jiajie, Wu, Shunquan, Tang, Lei, Xu, Xudong, Bai, Jie, Ding, Caicui, Chang, Yue, Yue, Long, Kang, Enming, He, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281826/
https://ncbi.nlm.nih.gov/pubmed/22363427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030353
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