Reciprocal Metabolic Perturbations in the Adipose Tissue and Liver of GPIHBP1-deficient Mice

OBJECTIVE: Gpihbp1-deficient mice (Gpihbp1(−/−)) lack the ability to transport lipoprotein lipase to the capillary lumen, resulting in mislocalization of LPL within tissues, defective lipolysis of triglyceride-rich lipoproteins, and chylomicronemia. We asked whether GPIHBP1 deficiency and mislocaliz...

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Main Authors: Weinstein, Michael M., Goulbourne, Christopher, Davies, Brandon S. J., Tu, Yiping, Barnes, Richard H., Watkins, Steven M., Davis, Ryan, Reue, Karen, Tontonoz, Peter, Beigneux, Anne P., Fong, Loren G., Young, Stephen G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281771/
https://ncbi.nlm.nih.gov/pubmed/22173228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.241406
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