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C-terminal Modification of Osteopontin Inhibits Interaction with the α(V)β(3)-Integrin

Osteopontin (OPN) is a multifunctional phosphorylated protein containing the integrin binding sequence Arg-Gly-Asp through which it interacts with several integrin receptors, such as the α(V)β(3)-integrin. OPN exists in many different isoforms differing in phosphorylation status that are likely to i...

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Bibliografiske detaljer
Main Authors: Christensen, Brian, Kläning, Eva, Nielsen, Mette S., Andersen, Mikkel H., Sørensen, Esben S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281738/
https://ncbi.nlm.nih.gov/pubmed/22179617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.277996
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