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Mechanisms of Rapid Induction of Interleukin-22 in Activated T Cells and Its Modulation by Cyclosporin A

IL-22 is an immunoregulatory cytokine displaying pathological functions in models of autoimmunity like experimental psoriasis. Understanding molecular mechanisms driving IL-22, together with knowledge on the capacity of current immunosuppressive drugs to target this process, may open an avenue to no...

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Autors principals: Rudloff, Ina, Bachmann, Malte, Pfeilschifter, Josef, Mühl, Heiko
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281663/
https://ncbi.nlm.nih.gov/pubmed/22170067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.286492
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