Tristetraprolin regulation of interleukin-22 production

Interleukin (IL)-22 is a STAT3-activating cytokine displaying characteristic AU-rich elements (ARE) in the 3′-untranslated region (3′-UTR) of its mRNA. This architecture suggests gene regulation by modulation of mRNA stability. Since related cytokines undergo post-transcriptional regulation by ARE-b...

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Publicat a:Sci Rep
Autors principals: Härdle, Lorena, Bachmann, Malte, Bollmann, Franziska, Pautz, Andrea, Schmid, Tobias, Eberhardt, Wolfgang, Kleinert, Hartmut, Pfeilschifter, Josef, Mühl, Heiko
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613560/
https://ncbi.nlm.nih.gov/pubmed/26486958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15112
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