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Calcium Binding to Leptospira Outer Membrane Antigen LipL32 Is Not Necessary for Its Interaction with Plasma Fibronectin, Collagen Type IV, and Plasminogen

LipL32 is the most abundant outer membrane protein from pathogenic Leptospira and has been shown to bind extracellular matrix (ECM) proteins as well as Ca(2+). Recent crystal structures have been obtained for the protein in the apo- and Ca(2+)-bound forms. In this work, we produced three LipL32 muta...

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Detalhes bibliográficos
Main Authors: Hauk, Pricila, Barbosa, Angela Silva, Ho, Paulo Lee, Farah, Chuck Shaker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281616/
https://ncbi.nlm.nih.gov/pubmed/22147698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.277210
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