Calcium Binds to LipL32, a Lipoprotein from Pathogenic Leptospira, and Modulates Fibronectin Binding

Tubulointerstitial nephritis is a cardinal renal manifestation of leptospirosis. LipL32, a major lipoprotein and a virulence factor, locates on the outer membrane of the pathogen Leptospira. It evades immune response by recognizing and adhering to extracellular matrix components of the host cell. Th...

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Bibliographic Details
Main Authors: Tung, Jung-Yu, Yang, Chih-Wei, Chou, Shao-Wen, Lin, Chien-Chih, Sun, Yuh-Ju
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823465/
https://ncbi.nlm.nih.gov/pubmed/19948735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006320
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