Varenicline Dose Dependently Enhances Responding for Nonpharmacological Reinforcers and Attenuates the Reinforcement-Enhancing Effects of Nicotine

INTRODUCTION: Varenicline (VAR), a partial nicotinic agonist, is one of the most effective smoking cessation pharmacotherapies. The therapeutic efficacy of VAR could be partly the result of substituting for and/or blocking the reinforcement-enhancing effects of nicotine (NIC). We assessed the effect...

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Main Authors: Levin, Melissa E., Weaver, Matthew T., Palmatier, Matthew I., Caggiula, Anthony R., Sved, Alan F., Donny, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281240/
https://ncbi.nlm.nih.gov/pubmed/21994342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntr213
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