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Indy Mutants: Live Long and Prosper

Indy encodes the fly homolog of a mammalian transporter of di and tricarboxylate components of the Krebs cycle. Reduced expression of fly Indy or two of the C. elegans Indy homologs leads to an increase in life span. Fly and worm tissues that play key roles in intermediary metabolism are also the pl...

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Bibliographic Details
Main Authors: Frankel, Stewart, Rogina, Blanka
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281209/
https://ncbi.nlm.nih.gov/pubmed/22363340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00013
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