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Indy Mutants: Live Long and Prosper

Indy encodes the fly homolog of a mammalian transporter of di and tricarboxylate components of the Krebs cycle. Reduced expression of fly Indy or two of the C. elegans Indy homologs leads to an increase in life span. Fly and worm tissues that play key roles in intermediary metabolism are also the pl...

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Bibliografiske detaljer
Main Authors: Frankel, Stewart, Rogina, Blanka
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281209/
https://ncbi.nlm.nih.gov/pubmed/22363340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00013
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